Cryo-EM Structure of astemizole-bound hERG Channel

Cryo-EM Structure of astemizole-bound hERG Channel Descriptor: 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine, Potassium voltage-gated channel subfamily H member 2 Authors: Miyashita, Y, Moriya, T, Kato, T, Kawasaki, M, Yasuda, Y, Adachi, N, Suzuki, K, Ogasawara, S, Saito, T, Senda, T, Murata, T. Deposit date: 2024-06-18 Release date: 2024-09-18 Last modified: 2024-11-27 Method: ELECTRON MICROSCOPY (3.29 Å) Cite: Improved higher resolution cryo-EM structures reveal the binding modes of hERG channel inhibitors. Structure, 32, 2024