Empirical type I error estimates of MAPIT.

Each entry represents type I error rate estimates as the proportion of p-values a under the null hypothesis based on 100 simulated continuous phenotypes for the normal test (or z-test) and the Davies method. These results are based on 100 simulated data sets using simulation model (i). Empirical size for the analyses used significance thresholds of α = 0.05, 0.01, and 0.001. Sample sizes were set to 1,000, 1,750, and 2,500. Values in the parentheses are the standard deviations of the estimates.