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Crystal Structure of human IL-1beta in complex with a low molecular weight antagonist

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Protein Data Bank Japan2024-03-27 更新2026-04-25 收录
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Crystal Structure of human IL-1beta in complex with a low molecular weight antagonist Descriptor: (S)-4'-hydroxy-3'-(6-methyl-2-oxo-3-(1H-pyrazol-4-yl)indolin-3-yl)-[1,1'-biphenyl]-2,4-dicarboxylic acid, Interleukin-1 beta Authors: Rondeau, J.-M, Lehmann, S, Koch, E. Deposit date: 2022-12-28 Release date: 2023-09-13 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.945 Å) Cite: Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1 beta. Nat Commun, 14, 2023
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2022-12-28
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