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Plasmodium falciparum 3D7 Raw sequence reads. Plasmodium falciparum 3D7

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NIAID Data Ecosystem2026-03-09 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA309323
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资源简介:
MMV007564, a benzimidazolyl piperidine previously identified in a cellular screen, is a novel antimalarial chemotype. To identify the genetic determinant of MMV007564 resistance, parasites were cultured in the presence of the compound to generate resistant lines. Whole genome sequencing revealed distinct mutations in the gene named Plasmodium falciparum cyclic amine resistance locus (pfcarl), encoding a conserved protein of unknown function. This study was conducted as part of the MDTIP Consortium project.
创建时间:
2016-01-20
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