A condensin-like dosage compensation complex acts at a distance to control expression throughout the genome

ChEBI2010-05-22 更新2026-07-21 收录

剂量补偿

染色质远程调控

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A condensin-like dosage compensation complex acts at a distance to control expression throughout the genome

创建时间：

2010-05-22

Binding of an X-specific condensin correlates with a reduction in active histone modifications at gene regulatory elements. Binding of an X-specific condensin correlates with a reduction in active histone modifications at gene regulatory elements

剂量补偿

表观遗传调控

Condensins are evolutionarily conserved protein complexes that are required for chromosome segregation during cell division and genome organization during interphase. In C. elegans, a specialized cond

NIAID Data Ecosystem40

Examination of DPY-30, DPY-27, SDC-3, DPY-26, MIX-1, SMC-4, ASH-2, RNA Polymerase II binding in wild type and DCC mutant embryos

剂量补偿

染色质分析

Here we exploit the essential process of X-chromosome dosage compensation to elucidate basic mechanisms that control the assembly, genome-wide binding, and function of gene regulatory complexes that

NIAID Data Ecosystem20

Facultative dosage compensation of developmental genes on autosomes in Drosophila and mammals [ChIP-seq Dmel]

剂量补偿

发育基因表观调控

Haploinsufficiency and aneuploidy are two phenomena, where alteration of gene dosage causes severe cellular defects ultimately resulting in developmental failures and disease. One remarkable exception

NIAID Data Ecosystem10

Sequence variation within similar cis-elements promotes context-specific functions of two Drosophila GA-binding transcription factors (ChIP-seq data set)

转录因子结合位点分析

剂量补偿

A key model for understanding how large transcription complexes are targeted is the Drosophila dosage compensation system in which the Male-Specific Lethal (MSL) transcription complex specifically ide

NIAID Data Ecosystem30

Ectopically expressed MSL2 females compared with normal females

剂量补偿

MSL复合物研究

We used H83M2 P element to ectopically expressed MSL2 protein in females to test if the novel formed MSL complex is the directly reason of dosage compensation Compare the MSL2 females with normal fema

NIAID Data Ecosystem10

A condensin-like dosage compensation complex acts at a distance to control expression throughout the genome

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