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The miRNA profiles of amniotic fluid-derived extracellular vesicles and fetal lung tissue of nitrofen-induced congenital diaphragmatic hernia rat model.

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Congenital diaphragmatic hernia (CDH) is a life-threatening anomaly with high morbidity and mortality. To investigate the pathogenesis of CDH, miRNA sequencing was performed using amniotic fluid-derived extracellular vesicles (AF-EVs) and fetal lung tissue of nitrofen-induced CDH rat model.

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