Three-Component Condensation for the Construction of Novel Spirooxindoles
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http://www.thieme-connect.com/DOI/DOI?10.1055/s-0032-1316836
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资源简介：
A new route for the synthesis of novel spirooxindoles from isocyanides, dialkyl acetylenedicarboxylates, and N-substituted isatylidene derivatives through [3+2] cycloaddition has been developed. This method has several advantages, such as high regioselectivity, high yields, readily available starting materials, and one-pot operations. The synthetic alkyne-containing spirooxindoles could also be used in the selective synthesis of triazole-containing spirocyclic compounds using a copper azide–alkyne cycloaddition (CuAAC) reaction.
提供机构：
© Georg Thieme Verlag
创建时间：
2013-03-01
