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RIP-seq experiment to evaluate the role of methylation of the spliceosome component LSM4 in the regulation of alternative splicing

ChEBI2023-05-31 更新2026-07-12 收录

RNA免疫沉淀测序

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数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-12369 数据链接链接失效反馈

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资源简介：

RIP-seq experiment to evaluate the role of methylation of the spliceosome component LSM4 in the regulation of alternative splicing

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创建时间：

2023-05-31

神经退行性机制

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GGC repeat expansion within NOTCH2NLC gene has been identified as the genetic cause of neuronal intranuclear inclusion disease (NIID). To understand the molecular pathogenesis of NIID, here we have es

NIAID Data Ecosystem70

Table_6_Differential alternative splicing genes and isoform co-expression networks of Brassica napus under multiple abiotic stresses.xlsx

植物非生物胁迫

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Alternative splicing (AS) is an important regulatory process that affects plant development and stress responses by greatly increasing the complexity of transcriptome and proteome. To understand how t

NIAID Data Ecosystem30

Table2_The nuclear GYF protein CD2BP2/U5–52K is required for T cell homeostasis.xlsx

T细胞稳态

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The question whether interference with the ubiquitous splicing machinery can lead to cell-type specific perturbation of cellular function is addressed here by T cell specific ablation of the general U

NIAID Data Ecosystem20

Comparison of PPIE knockdown in HEK293T cells compared to scrambled shRNA control. Comparison of PPIE knockdown in HEK293T cells compared to scrambled shRNA control

基因功能研究

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HEK293T cells transduced with shRNA from MISSION library TRCN0000049368 using lentiviral delivery system. HEK293T cells transduced with scrambled shRNA, gifted from Dr. Mauricio Reginato. Tara L Davis

NIAID Data Ecosystem30

SHAPE datasets from manuscript: Modulation of pre-mRNA structure by hnRNP proteins regulates alternative splicing of MALT1

RNA测序分析

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Normalized SHAPE reactivity for the MALT1 M1 minigene RNA constructs (wildtype, variant 1, and variant 2) reported in the manuscript titled 'Modulation of pre-mRNA structure by hnRNP proteins regulate

Zenodo2021-12-19 更新20

RIP-seq experiment to evaluate the role of methylation of the spliceosome component LSM4 in the regulation of alternative splicing

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