Risk of cardiovascular events in patients with Down Syndrome.

DS = Down Syndrome; MI = myocardial infarction; TIA = transient ischemic attack.
Cerebrovascular events include stroke (ischemic, hemorrhagic or unspecified) or transient ischemic attack.
Coronary events include myocardial infarction or angina.
Model 1: adjusted for sex
Model 2: adjusted for sex and overall cardiovascular risk
(Overall cardiovascular risk is represented by a variable that includes the presence of any of congenital heart disease, cardiac arrhythmia, pulmonary hypertension, hypertension, diabetes mellitus, sleep apnea, smoking or Moyamoya disease)
* P<0.05
** P<0.01
*** P<0.001
(Data are n [%] patients unless otherwise indicated).