Cryo-EM structure of substrate engaged p97-Ufd1-NPL4-Faf1 complex (NPL4 focused)

Cryo-EM structure of substrate engaged p97-Ufd1-NPL4-Faf1 complex (NPL4 focused) Descriptor: Nuclear protein localization protein 4 homolog, Ubiquitin, Ubiquitin recognition factor in ER-associated degradation protein 1, ... Authors: Liao, Z, Martin, A. Deposit date: 2026-03-11 Release date: 2026-04-22 Last modified: 2026-04-29 Method: ELECTRON MICROSCOPY (4.28 Å) Cite: Faf1 accelerates p97-mediated protein unfolding by promoting ubiquitin engagement. Biorxiv, 2025