Differentially expressed genes in response to PGC-1α-overexpression in cultured muscle cells.

Microarray analysis was performed on six cultured skm cell samples from three independent experiments, three transduced with Ad-GFP and three with Ad-PGC-1α adenovirus. The table lists the 53 regulated gene transcripts selected on the basis of the fold change (FC) and ordered by the magnitude of the absolute FC. Replicated genes, which occurred more than once in the microarray, were filtered: those appearing first in the list were arbitrarily chosen. The first column lists the NCBI Reference Sequence (RefSeq) accession number of the transcripts, the second the gene symbol, the third the description of the gene, the fourth the FC (with a positive symbol for upregulated genes and a negative symbol for downregulated ones) and the fifth the significance of differences as estimated by a paired t-test.