Retinoic acid signaling regulates monocyte differentiation into dendritic cells or macrophages. We used microarrays to uncover gene expression changes associated with retinoic acid exposure in mouse m

NIAID Data Ecosystem40

Hydrogels with stiffness-degradation spatial patterns allow the emergence of ...

生物材料设计

组织工程

In nature, tissues are patterned, but most biomaterials used in human applications are not. Patterned biomaterials offer the opportunity to mimic spatially segregating...

B2FIND20

Microfluidic Perfusion for Regulating Diffusible Signaling in Stem Cells

细胞分化调控

微流控细胞培养

BackgroundAutocrine & paracrine signaling are widespread both in vivo and in vitro, and are particularly important in embryonic stem cell (ESC) pluripotency and lineage commitment. Although autocrine

NIAID Data Ecosystem50

Inhibition of DYRK1B suppresses inflammation in allergic contact dermatitis model and Th1/Th17 immune response

细胞分化调控

激酶靶点干预

To investigate the inhibition effect of DYRK1B kinase function on human naïve CD4+ T cell differetionation which stimulated under Treg polarizing condition for 24 hours. We then performed gene express

NIAID Data Ecosystem30

Sox11 inhibits osteoblast differentiation of adipose tissue derived mesenchymal stem cell

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