A Straightforward Synthesis of Enantiopure (1S,2R)-Ephenamine
收藏Figshare2020-12-01 更新2026-04-28 收录
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https://figshare.com/articles/dataset/A_Straightforward_Synthesis_of_Enantiopure_1S_2R_-Ephenamine/14304065
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资源简介:
An enantioselective six-step synthesis of (1S,2R)-ephenamine starting from readily available chiral amino acid is disclosed presenting 26% overall yield and high optical purity. The use of chiral phenylglycine as starting material was also studied and did not present satisfactory results due to a very sensitive a-carbonyl/benzylic stereogenic center that, in our hands, led to racemization.
创建时间:
2020-12-01



