CDK9 inhibitor induces the apoptosis of acute lymphocytic leukemia by inhibiting c-Myc-mediated glycolytic metabolism
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE166339
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Purpose:the inhibitory effect of CDK9i on the energy metabolism of B-ALL cells remains unclear. To address this question, we collected SNS-032- and DMSO-treated cells for RNA sequencing Methods:REH cells were seeded at a density of 1× 106 cells/ml and treated with 200nm SNS_032 or DMSO for 24h. Results:CDK9i perturbs the glycolytic metabolism of B-ALL cells in vitro. REH total mRNA profiles treated with 200nm SNS_032 or DMSO for 24h.
创建时间：
2021-03-23
