Clinical events triggering switch after 44 weeks on ART in patients monitored without CD4 cell counts (CDM).

Note: SBI = severe bacterial infection; OHL = oral hairy leukoplakia; ERC = Endpoint Review Committee (blinded to randomised group). Data not shown for events with only 1 associated switch: visceral herpes simplex, HIV encephalopathy, recurrent pneumonia, weight loss+persistent fever, weight loss+oral candida+SBI, oral candida+OHL, pulmonary TB+SBI, HIV nephropathy, OHL). Additional new/recurrent WHO events which occurred during the first year on ART are included in the main trial report[4], but not here as switch to second-line for first-line failure only occurred after 1 year.