Rh(III)-Catalyzed Synthesis of <i>N</i>‑Unprotected Indoles from Imidamides and Diazo Ketoesters via C–H Activation and C–C/C–N Bond Cleavage

The synthesis of N-unprotected indoles has been realized via Rh­(III)-catalyzed C–H activation/annulation of imidamides with α-diazo β-ketoesters. The reaction occurs with the release of an amide coproduct, which originates from both the imidamide and the diazo as a result of CN cleavage of the imidamide and C–C­(acyl) cleavage of the diazo. A rhodacyclic intermediate has been isolated and a plausible mechanism has been proposed.