Ptges

ENCODES a protein that exhibits prostaglandin-D synthase activity; prostaglandin-E synthase activity; glutathione binding (ortholog); INVOLVED IN chronic inflammatory response; prostaglandin biosynthetic process; response to calcium ion; PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH Barrett's esophagus; Experimental Arthritis; Inflammation; FOUND IN perinuclear region of cytoplasm; cytoplasm (ortholog); membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid

编码一种表现出前列腺素-D合酶活性、前列腺素-E合酶活性及谷胱甘肽结合（同源）活性的蛋白质；参与慢性炎症反应、前列腺素生物合成过程、钙离子反应；参与乙酰水杨酸药效动力学途径、安替比林药物途径、花生四烯酸代谢途径；与Barrett食道炎、实验性关节炎、炎症相关；存在于细胞质核周区域、细胞质（同源）、膜（同源）中；与2,2',4,4'-四溴二苯醚、2,3,7,8-四氯二苯并-对-二恶英、2,4,6-三硝基苯磺酸相互作用。