Test No. 231: Amphibian Metamorphosis Assay

Organisation for Economic Co-operation and Development2026-04-04 收录

甲状腺激素干扰

两栖动物变态

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This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is ...

RNA-Seq of zebrafish embryos (96hpf) treated with different concentrations of 6-Propyl-2-thiouracil (6-PTU) below acute toxicity levels against untreated control groups. RNA-Seq of zebrafish embryos (96hpf) treated with different concentrations of 6-Propyl-2-thiouracil (6-PTU) below acute toxicity levels against untreated control groups

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甲状腺激素干扰

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Healthy men received 75 5g/d of T3 for 14 days. Microbiopsies of vastus lateralis skeletal muscle were performed before and after the treatment. For microarray experiments, we used samples from five s

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Test No. 231: Amphibian Metamorphosis Assay

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