官方服务:
资源简介:
On targeting specificity of Cas12b nucleases
应用场景:
创建时间:
2022-02-25
相关数据集
NGS data for Systematic Discovery of Novel Type V CRISPR-Cas Systems. Escherichia coli
For the paper "Systematic discovery of Type V CRISPR-Cas systems expands the functional and evolutionary diversity of RNA-guided nucleases." Contains DNA-sequencing reads containing repeat-spacer-repe
NIAID Data Ecosystem90
RNA-seq of MUTZ3 cells in experiments to investigate EVI1 regulation
We investigated whether GATA2 enhancer-driven transcription of EVI1 in inv(3)/t(3;3) is reversible in leukemia cells. In primary inv(3)/t(3;3) AML, immature CD34+CD15- cells can be discriminated from
NIAID Data Ecosystem60
polyclonal_editing_fastq_files
FASTQs from amplicon sequencing of cDNA and gDNA after CRISPR editing of putative regulatory and control variants. Files are contained in tarballs grouped by sequencing run. 20190312 is a rerun of the
DataCite Commons2020-08-26 更新30
Engineering a miniaturized SaCas9 adenine base editor with reduced RNA off-targets and increased on-target DNA editing efficiencies. Protein domain-altered adenine base editors
We compared the editing profile of circularly permuted and domain inlaid Cas9 base editors, and found that on-target editing can be largely maintained following their intradomain insertion, but that s
NIAID Data Ecosystem80
Transcriptional profiling for CRISPR activation of a myeloma-preferential dependency
Clinical progress in multiple myeloma (MM), an incurable plasma cell (PC) neoplasia, has been driven by therapies which have limited applications beyond MM/PC neoplasias and do not target specific onc
NIAID Data Ecosystem50



