Potential biomarkers detected by NMR and MS, metabolic pathways, as well as fold changes between different groups (n = 6).

Note: HFD, Con, Cur1, Cur2, Lov represent hyperlipidemia, control, curcumin (40 mg/kg), curcumin (80 mg/kg), lovastatin (30 mg/kg) groups, separately. TMA short for trimethylamine; DMA short for dimethylamine; MA short for methylamine; MMA short for methylmalonate; CP represent creatine phosphate; Leu/ILE short for leucine and isoleucine. XXX/YYY means integral of metabolite in XXX group was divided by that of YYY group. The ratio over 1.00 indicated an increase, while ratio less than 1.00 indicated a decrease. Statistical analysis was performed by one-way analysis of variance followed by LSD test.*p**pPotential biomarkers detected by NMR and MS, metabolic pathways, as well as fold changes between different groups (n = 6).