Cleavable Hydrophobic Derivatization Strategy for Enrichment and Identification of Phosphorylated
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https://escience.org.cn/metadata/detail?cstrId=CSTR:17970.11.A001G.202003.000952&id=774e74221ac511e980780242ac120006:CSTR:A0006.11.A001G.202003.000952
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资源简介:
Herein, a cleavable hydrophobic derivatization (CHD) strategy was established for the enrichment and identification of pLys peptides. By CHD, 2,5-dioxopyrrolidin-1-yl-3-(decyldisulfanyl)propanoate (Dec-disulf-NHS) was synthesized to react with lysine dephosphorylated peptides, and then the derived peptides were captured by a C18 column, followed by the cleavage of hydrophobic chain to leave the specific label on the target peptides.
提供机构:
国家人口健康科学数据中心
创建时间:
2020-11-24



