Establishment of a mouse IgA nephropathy model with the MBP-20-peptide fusion protein.
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The epitope-specific mAb bound to the renal biopsy section from an immunoglobulin-A nephropathy patients. There is strong labeling of glomeruli and weak labeling of tubular epithelial cells in 82% cases of immunoglobulin-A nephropathy. The mAb also bound to mice with experimental immunoglobulin-A nephropathy induced by immunization with the epitope..
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2010-01-01



