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Subtle variations in Pten dose determine cancer susceptibility: Gene expression profiling of a Ptenhy/+ mouse model

ChEBI2010-02-21 更新2026-07-21 收录

肿瘤遗传学

小鼠模型基因表达

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-20316 数据链接链接失效反馈

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Subtle variations in Pten dose determine cancer susceptibility: Gene expression profiling of a Ptenhy/+ mouse model

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创建时间：

2010-02-21

神经纤维瘤

肿瘤遗传学

Plexiform neurofibromas (PN) are benign nerve sheath Schwann cell tumors, common in patients with neurofibromatosis type 1 (NF1), that are characterized by biallelic mutations in the NF1 tumor suppres

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Table2_Novel and recurrent genetic variants of VHL, SDHB, and RET genes in Chinese pheochromocytoma and paraganglioma patients.XLSX

肿瘤遗传学

基因变异分析

Background: Pheochromocytoma and paraganglioma (PPGL) are rare neuroendocrine tumors arising from chromaffin cells in the adrenal medulla and extra-adrenal ganglia, respectively. The study was aimed t

NIAID Data Ecosystem50

Genetic analysis using genomic representations

肿瘤遗传学

基因表达技术

Analysis of the genetic changes in human tumors is often problematical because of the presence of normal stroma and the limited availability of pure tumor DNA. However, large amounts of highly reprodu

PubMed Central1998-04-14 更新40

Monoallelic loss of the imprinted gene Grb10 promotes tumor formation in irradiated Nf1+/- mice

印迹基因功能

肿瘤遗传学

Imprinted genes are expressed from only one parental allele and heterozygous loss involving the expressed allele is sufficient to produce complete loss of protein expression. Genetic alterations are c

DataONE2020-06-24 更新70

Discriminating activities of DEAD-Box Helicase 41 from myeloid malignancy-associated germline variants by genetic rescue

肿瘤遗传学

基因功能验证

Although DEAD-box helicase 41 (DDX41) is implicated in oncogenic and innate immune mechanisms, there are many unanswered questions about how the ever-increasing spectrum of genetic variants impacts DD

NIAID Data Ecosystem50

Subtle variations in Pten dose determine cancer susceptibility: Gene expression profiling of a Ptenhy/+ mouse model

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