JAK3 in complex with a covalent EGFR inhibitor
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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JAK3 in complex with a covalent EGFR inhibitor Descriptor: N-[3-(2-{3-amino-6-[1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl]pyrazin-2-yl}-1H-benzimidazol-1-yl)phenyl]propanamide, TYROSINE-PROTEIN KINASE JAK3 Authors: Debreczeni, J.E, Hennessy, E.J, Chuaquini, C, Ashton, S, Coclough, N, Cross, D.A.E, Eberlein, C, Gingipalli, L, Klinowska, T.C.M, Orme, J.P, Sha, L, Wu, X. Deposit date: 2014-09-16 Release date: 2016-01-13 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3 Å) Cite: Utilisation of Structure Based Design to Identify Novel, Irreversible Inhibitors of the Epidermal Growth Factor Receptor (Egfr) Harboring the Gatekeeper T790M Mutation To be Published
创建时间：
2014-09-16
