Role of AcuK and AcuM transcription factors in dimorphic fungus Talaromyces marneffei: Analysis of target gene expression and macrophage interaction

To identify the role of acuK and acuM transcription factors in <i>Talaromyces marneffei</i>, we examined the ability of the <i>acuK</i> and <i>acuM</i> deletion mutants to (i) regulate target genes involved in iron metabolism and gluconeogenesis, and to (ii) interact with host macrophage THP1 cells.