Transcriptional control of amino acid biosynthesis

We transcriptional profiled four transcription factor knockout strains in S288C background growing in YNB media + 2% glucose to understand the link between mRNA levels and our measured C13 fluxes of amino acid biosynthesis我们对处于S288C遗传背景下、在添加2%葡萄糖的YNB培养基（Yeast Nitrogen Base）中培养的四株转录因子敲除菌株进行了转录谱分析，以探究mRNA水平与我们所测得的氨基酸生物合成碳13通量之间的关联。