Hypoxia-dependence of NESP55 immunoreactivity in clinical variants of neuroblastoma and in ganglioneuroma.

NESP55 expression was evaluated by immunohistochemistry and hypoxia dependence by its co-expression with VEGFA and/or IGF2, as determined with in situ hybridization performed on sections consecutive to those used for the NESP55 analyses.Abbreviations and symbols: n: number of cases;§negative results are based on two independent experiments;*number of tumors subjected to chemotherapy prior to sampling; >18 mo: more than 18 months of age at diagnosis.