Tumor grade and semi-quantitative measurement of AQP5 labeling intensity and proportion in the invasive ductal carcinoma with or without lymph node metastasis.

Tumor grade was determined by modified Bloom-Richardson-Elston grading system. Immunolabeling intensity of AQP5 was scored as negative (-), weak (score 1), moderate (score 2), and strong (score 3) by expert pathologists. Proportion was the approximate numbers of AQP5-positive tumor cells among the total tumor cells, scored as negative(-), <33% (score 1), 34%–66% (score 2), and>67% (score 3). N.A., not available.