Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

ChEBI2010-07-11 更新2026-07-21 收录

造血调控

急性髓系白血病

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Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

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2010-07-11

Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia [barcode-seq SG12]

急性髓系白血病

耐药性机制

Targeting the MYST acetyltransferases are an exciting therapeutic opportunity in acute myeloid leukaemia (AML). Here we define the individual and combined contribution of KAT6A, KAT6B and KAT7, in ran

NIAID Data Ecosystem90

Supplementary Table 2 from Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia

急性髓系白血病

转录因子调控

Transcription Factor Enrichment Analysis of MOLM13 Bulk RNA-Seq (24 Hours After Drug Treatment)

Figshare2023-07-05 更新40

MED16 negatively regulates erythropoiesis and myelopoiesis through modulation of chromatin accessibility. MED16 negatively regulates erythropoiesis and myelopoiesis through modulation of chromatin accessibility

造血调控

染色质可及性分析

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem20

RNA sequencing expression analysis of murine MLL-AF9;NRAS acute myeloid leukemia cells silenced for E2-2.

急性髓系白血病

RNA测序

We investigated the role of the transcriptional regulators Id2 and E2-2 (encoded by Tcf4) in the context of MLL-rearranged acute myeloid leukemia (AML). Using an AML mouse model driven by a Tet-off in

干细胞与再生医学数据中心2022-02-20 更新80

Role of Branched Chain Amino Acid Transaminase 1 (BCAT1) in Acute Myeloid Leukemia [expression_BCAT1-KD #2]

急性髓系白血病

BCAT1

The branched chain amino acid (BCAA) pathway and high levels of BCAA transaminase 1 (BCAT1) have recently been associated with aggressiveness in several cancer entities. However, the mechanistic role

NIAID Data Ecosystem30

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

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