CARDIOMED Registry — Anonymised Dataset: Haematocrit and in-hospital mortality in ADHF at 2,600 m a.s.l.

# CARDIOMED Registry — Anonymised Dataset## Haematocrit and in-hospital mortality in acute decompensated heart failure at 2,600 m a.s.l.

**Associated publication:**Rodríguez Lima DR, Pavia-Velandia PX, Carreño-Jaimes M, León-León NG, Campo-Bautista EM,Calderon-Barrera JN, Paez-Rincon JD.*Haematocrit and in-hospital mortality in acute decompensated heart failure at 2,600 m above sea level:a retrospective analysis of a prospective registry from Bogotá, Colombia.*Clinical Research in Cardiology, [year]. doi: [to be assigned upon acceptance]

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## Dataset description

This dataset contains anonymised individual-patient data from the CARDIOMED prospective registry,Hospital Universitario Mayor-Méderi, Bogotá, Colombia (2,600 m above sea level).

| Attribute | Value ||-----------|-------|| **Patients** | N = 886 (analytic cohort with outcome data) || **Enrolment period** | January 2022 – December 2025 || **Setting** | Single-centre university hospital, Bogotá, Colombia (2,600 m a.s.l.) || **Diagnosis** | Acute decompensated heart failure (ADHF), 2021 ESC criteria || **Primary outcome** | In-hospital death || **Ethics** | CEI-HUM DVO005 2333-CV1731 (Hospital Universitario Mayor-Méderi / Universidad del Rosario) |

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## Files

| File | Description ||------|-------------|| `CARDIOMED_Anonymised.csv` | Main dataset — 886 rows × 41 variables || `CARDIOMED_Codebook.csv` | Data dictionary with type, values, units, and notes for each variable || `README.md` | This file |

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## Variable groups

| Group | Variables ||-------|-----------|| **Demographics** | patient_id, age_years, sex, sex_label || **Haematology** | haematocrit_pct, haemoglobin_gdl || **Vital signs** | systolic_bp_mmhg, heart_rate_bpm || **Clinical severity** | nyha_class || **Comorbidities** | hypertension, diabetes_t2, copd, chronic_kidney_disease, atrial_fibrillation || **HF aetiology** | aetiology_ischaemic, aetiology_hypertensive, aetiology_valvular || **Echocardiography** | lvef_pct, tapse_mm, spap_mmhg, tapse_spap_ratio, hf_phenotype || **Laboratory** | creatinine_mgdl, sodium_meql, potassium_meql, bun_mgdl, troponin_ngl, nt_probnp_pgml || **Ferrokinetics (subset n=249)** | tsat_pct, ferritin_ngml, iron_deficiency_esc2021 || **Outcomes** | inhospital_death, icu_admission, los_days, killip_class_discharge, levosimendan, cardiogenic_shock, composite_outcome || **Derived — altitude** | altitude_anaemia, who_anaemia, altitude_anaemia_gap, haematocrit_quintile |

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## Key thresholds applied

| Threshold | Definition | Reference ||-----------|------------|-----------|| **Altitude anaemia** | Hct <44% (males), <38% (females) | Gómez-García et al. *Biomédica* 2010 || **WHO anaemia (Hb-derived Hct)** | Hct <39% (males, Hb <13 g/dL), <36% (females, Hb <12 g/dL) | WHO 2011; Hct ≈ Hb × 3 || **Altitude anaemia gap** | WHO Hb-derived Hct normal BUT below altitude-adjusted lower limit | This study || **Iron deficiency ESC 2021** | Ferritin <100 ng/mL OR (ferritin 100–299 AND TSAT <20%) | McDonagh et al. *Eur Heart J* 2021 || **PH** | SPAP ≥35 mmHg | ESC 2022 || **HF phenotype** | HFrEF <40%, HFmrEF 40–49%, HFpEF ≥50% | ESC 2021 |

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## Missing data summary

| Variable | Available | Missing ||----------|-----------|---------|| Haematocrit / Haemoglobin | 882/886 (99.5%) | 0.5% || LVEF | 783/886 (88.3%) | 11.7% || SPAP | 606/886 (68.4%) | 31.6% || TAPSE | 497/886 (56.1%) | 43.9% || Troponin | 651/886 (73.5%) | 26.5% || NT-proBNP | 331/886 (37.4%) | 62.6% || Transferrin saturation | 257/886 (29.0%) | 71.0% || Ferritin | 278/886 (31.4%) | 68.6% || Ferrokinetic sub-study (TSAT + ferritin) | 249/886 (28.1%) | 71.9% |

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## Anonymisation

- Original REDCap `record_id` replaced with sequential `patient_id` (1–886).- All admission and discharge dates removed.- Hospital, physician, and insurance identifiers removed.- Only 314 REDCap variables are exported; the 41 retained here represent those used in the primary analysis.- Re-identification risk was assessed as minimal given the absence of dates, geographic sub-unit data,  and rare disease combinations. Ethics approval includes secondary use for research purposes.

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## Suggested citation

Rodríguez Lima DR et al. CARDIOMED Registry — Anonymised Dataset [dataset].Zenodo. https://doi.org/10.5281/zenodo.[RECORD_ID]

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## Licence

Creative Commons Attribution 4.0 International (CC BY 4.0).You are free to share and adapt the material for any purpose provided appropriate credit is given.https://creativecommons.org/licenses/by/4.0/

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## Contact

David René Rodríguez Lima, MD, [e-mail]: 0000-0002-7089-018XCardiac and Thoracic Institute, Méderi Research Center (CIMED)Hospital Universitario Mayor-Méderi / Universidad del RosarioBogotá, Colombia