We provide examples of the next-generation sequencing results obtained after analyzing sgRNAs (single guide RNAs) isolated from an input library and from parasites three passages after transfection. s
Malaria is spread by the transmission of sexual stage parasites, called gametocytes. However, with Plasmodium falciparum, gametocytes can only be detected in peripheral blood when they are mature and
Single-nucleotide variations (SNVs) in RNA, arising from co- and post-transcriptional phenomena including transcription errors and RNA-editing, are well studied in a range of organisms. In the malaria