Effects of anti-AapBrpt1.5 MAbs on different S. epidermidis strains.

a. “Relative biofilm formation” of the strains cultured in the presence of each MAb (10 µg/mL) in polystyrene plates was calculated by dividing the mean density of MAb-treated biofilms by that of untreated biofilms. “-” means no biofilm formation was observed.b. Planktonic aggregation of the strains statically cultured in the presence of each MAb (10 µg/mL) was described using “+++”, “++”, “+”, or “−”, which means that very many, many, a few, or no bacterial clusters were observed, respectively.c. Biofilm formation by the strains without treatment was described using “++”, “+”, “+/−”, or “−”, which means that strong, weak, slight, or no biofilm formation was observed in polystyrene plates, respectively.d. Cell aggregation of the strains without treatment was described using “+” or “−”, which means that a few or no bacterial clusters were observed, respectively.e. The clinical strains of S. epidermidis were obtained from Zhongshan Hospital and Ruijin Hospital, Shanghai, China.