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NIL-TDS

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP161022
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RNA interference (RNAi) is an effective natural process in which small RNAs mediate endonucleolytic slicing of complementary target mRNAs. Despite the potential of RNAi in human therapeutics and crop bio-protection, analytical platforms to quantitatively validate the slicing activities of small RNAs are lacking. Here we present NIL-TDS, a method that combines RNA-ligase mediated PCR with Nanopore Sequencing for rapid and highly accurate identification of sRNA-mediated slicing.
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2025-01-23
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