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Targeting the unwindosome by mebendazole is a vulnerability of chemoresistant hepatoblastoma

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NIAID Data Ecosystem2026-03-14 收录
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We identified mebendazole as a drug to circumvent chemoresistance in hepatoblastoma cell lines that are resistant to cisplatin. In order to identify the mechanistic basis of mebendazole function, we performed gene expression analysis of three mebendazole-treated hepatoblastoma cell lines. Comparative gene expression profiling analysis of RNA-seq data from mebendazole-treated hepatoblastoma cell lines

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2022-10-27
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