Crystal structure of human wild type STING in complex with 2'-3'-cyclic-GMP-7-deaza-AMP
收藏Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal structure of human wild type STING in complex with 2'-3'-cyclic-GMP-7-deaza-AMP Descriptor: 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{S},15~{R},17~{R},18~{R})-8-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)-3,9,12,18-tetrakis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-1~{H}-purin-6-one, Stimulator of interferon protein Authors: Boura, E, Smola, M, Brynda, J. Deposit date: 2019-06-20 Release date: 2019-11-27 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations. J.Med.Chem., 62, 2019
创建时间:
2019-06-20



