Effect of metronidazole on vaginal microbiota associated with asymptomatic bacterial vaginosis

WGS was conducted on DNA obtained from 20 vaginal swabs collected at four-time points over a period of 12 months from five randomly selected African-American (AA) women. The baseline visit (first-time point) included all women who were diagnosed with asymptomatic BV and were untreated. All subjects were tested subsequently once every two months and received a course of metronidazole for each episode of BV during the 12 months period.