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A Mononuclear Manganese(II) Complex Demonstrates a Strategy To Simultaneously Image and Treat Oxidative Stress

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Figshare2017-01-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/A_Mononuclear_Manganese_II_Complex_Demonstrates_a_Strategy_To_Simultaneously_Image_and_Treat_Oxidative_Stress/2254345
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A manganese­(II) complex with a ligand containing an oxidizable quinol group serves as a turn-on sensor for H2O2. Upon oxidation, the relaxivity of the complex in buffered water increases by 0.8 mM–1 s–1, providing a signal that can be detected and quantified by magnetic resonance imaging. The complex also serves as a potent antioxidant, suggesting that this and related complexes have the potential to concurrently visualize and alleviate oxidative stress.
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2017-01-02
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