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TGF-beta Sma/Mab signaling regulates a set of genes in oocytes associated with reproductive aging and another set in L4 associated with body size growth

ChEBI2010-09-01 更新2026-07-21 收录

衰老分子机制

发育生长调控通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-23509 数据链接链接失效反馈

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TGF-beta Sma/Mab signaling regulates a set of genes in oocytes associated with reproductive aging and another set in L4 associated with body size growth

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创建时间：

2010-09-01

衰老分子机制

MicroRNA调控

MicroRNAs (miRNAs) have been implicated in gene regulation in many complex processes, including aging. Moreover, expression levels of many miRNAs are altered during aging, though we know little about

NIAID Data Ecosystem70

Impact of cognitive performance and normal aging on transcriptomic changes in the prefrontal cortex of rats. Impact of cognitive performance and normal aging on transcriptomic changes in the prefrontal cortex of rats

衰老分子机制

转录组学分析

We investigated how cognitive stimulation impacts gene expression in the prefrontal cortex (PFC), a brain region known to regulate higher cognitive functions including the control of attention, in you

NIAID Data Ecosystem60

Additional file 3: of Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways

线粒体应激反应

衰老分子机制

Table S3. GO term enrichment for genes upregulated and downregulated in nuo-6 mutants and restored to wild-type in nuo-6;atfs-1 mutants. (XLSX 17 kb)

Figshare2018-12-19 更新40

Summary of DAF-16::GFP Nuclear Localization Data.

衰老分子机制

胰岛素信号通路

Animals were scored for presence of nuclear puncta after treatment with DMSO, daf-2(RNAi), FLA or following a 2 hour heat-shock incubation at 37°C. A Student's T-Test was used to determine statistical

NIAID Data Ecosystem70

Persistent JunB Activation in Fibroblasts Disrupts Stem Cell Niche Interactions Enforcing Skin Aging [RNA-seq]. Persistent JunB Activation in Fibroblasts Disrupts Stem Cell Niche Interactions Enforcing Skin Aging [RNA-seq]

衰老分子机制

成纤维细胞衰老

Fibroblasts residing in the connective tissue of all organs constitute the stem cell niche particularly in connective tissue rich organs like skin. Though the impact of the connective tissue resident

NIAID Data Ecosystem50

TGF-beta Sma/Mab signaling regulates a set of genes in oocytes associated with reproductive aging and another set in L4 associated with body size growth

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