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Resuscitated transcriptional network of a spurious transcription factor potentially facilitates transcriptional rewiring and adaptive evolution.

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NIAID Data Ecosystem2026-03-14 收录
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We report the ChIP-seq profiling of a spurious transcriptional factor Sef1 in non-typical model yeast species, Lachancea kluyveri, and show that LkSef1 targets many TCA cycle and many others genes but has very limited regulatory effects to these target genes. Overall design: LkSef1 ChIP-seq analysis was performed from three biological replicates of YPD- and YPGly-grown Sef1-TAP tagged cells, using Illumina NextSeq500 sequencer.

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2022-12-20
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