Zinc increases hormone receptor expression in human ovarian granulosa cells and gene profiling

To investigate the critical role of the trace element zinc in the expression of resistance to oxidative stress and hormonal responses in human ovarian granulosa cells (GCs). To investigate the critical role of the trace element zinc in the expression of antioxidant stress and hormonal responses in human ovarian granulosa cells (GCs). Overall design: In this study gradient centrifugation was used to successfully isolate human primary ovarian GCs. After extinction treatment, changes in oxidative stress levels and hormone-receptive expression in glutamatergic cells were sought. Examining the effect of zinc on the viability of ovarian granulosa cells in a zinc-deficlient micro environment.