Investigation of bone marrow microenvironment-induced drug resistance in acute lymphoblastic leukemia (ALL)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE200039
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Bulk RNA-seq of B-ALL cells cocultured with bone marrow-mesenchymal stem cells (BM-MSC) identified that B-ALL acquire epithelial-mesenchymal transition (EMT) properties by interacting with primary bone marrow-mesenchymal stem cells (BM-MSC) and scRNA-seq dissected the hybrid cluster of adherent B-ALL (Adh B-ALL) harboring B-ALL and BM-MSC features induced by EMT program Integrative analysis of transcriptome in ALL cells interacting with BM-MSC using bulk RNA-seq and single cell RNA-seq
创建时间：
2023-10-03
