five

A Metal- and Azide-Free Multicomponent Assembly toward Regioselective Construction of 1,5-Disubstituted 1,2,3-Triazoles

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https://figshare.com/articles/dataset/A_Metal_and_Azide_Free_Multicomponent_Assembly_toward_Regioselective_Construction_of_1_5_Disubstituted_1_2_3_Triazoles/2130061
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The construction of 1,5-disubstituted 1,2,3-triazoles has been effected through the cascade dual C–N bond formation, N–N bond formation and an acyl migration-based C–C bond formation via the three-component reactions of enaminones, tosylhydrazine and primary amines. This metal- and azide-free, regioselective synthetic method proceeds in the presence of only molecular iodine.
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2016-02-13
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