Optimization of spirocyclic proline tryptophanhydroxylase-1 inhibitors
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Optimization of spirocyclic proline tryptophanhydroxylase-1 inhibitors Descriptor: (3S)-8-(2-amino-6-{(1R)-1-[5-chloro-3'-(methylsulfonyl)[1,1'-biphenyl]-2-yl]-2,2,2-trifluoroethoxy}pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane-3-carboxylic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETONITRILE, ... Authors: Stein, A.J, Goldberg, D.R, De Lombaert, S, Holt, M.C. Deposit date: 2016-10-20 Release date: 2017-01-25 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
创建时间：
2016-10-20
