five

Plasma profiling of miRNAs in mouse model of osteosarcoma.. Mus musculus

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA273477
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Osteosarcoma (OS) is the primary bone tumor in children and young adults. Currently, there are no reliable, non-invasive biological markers to detect the presence or progression of disease, assess therapy response, or provide upfront prognostic insights. Using a qPCR-based platform that analyzes more than 750 miRNAs, we analyzed control and diseased-associated plasma from a genetically engineered mouse model of OS to identify a profile of four plasma miRNAs. Overall design: Plasma from mice with OS were profiled for miRNAs and compared with the profile of plasma from disease-free mice
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2015-01-23
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