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NEDD4 HECT with covalently bound indole-based inhibitor

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5c91
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资源简介:
NEDD4 HECT with covalently bound indole-based inhibitor Descriptor: E3 ubiquitin-protein ligase NEDD4, methyl (2E)-4-{[(5-methoxy-1,2-dimethyl-1H-indol-3-yl)carbonyl]amino}but-2-enoate Authors: Span, I, Smith, A.T, Kathman, S, Statsyuk, A.V, Rosenzweig, A.C. Deposit date: 2015-06-26 Release date: 2015-09-30 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.44 Å) Cite: A Small Molecule That Switches a Ubiquitin Ligase From a Processive to a Distributive Enzymatic Mechanism. J. Am. Chem. Soc., 137, 2015
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2015-06-26
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