NEDD4 HECT with covalently bound indole-based inhibitor

NEDD4 HECT with covalently bound indole-based inhibitor Descriptor: E3 ubiquitin-protein ligase NEDD4, methyl (2E)-4-{[(5-methoxy-1,2-dimethyl-1H-indol-3-yl)carbonyl]amino}but-2-enoate Authors: Span, I, Smith, A.T, Kathman, S, Statsyuk, A.V, Rosenzweig, A.C. Deposit date: 2015-06-26 Release date: 2015-09-30 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.44 Å) Cite: A Small Molecule That Switches a Ubiquitin Ligase From a Processive to a Distributive Enzymatic Mechanism. J. Am. Chem. Soc., 137, 2015