Zoltan Maliga (2014) CIL:43759, Homo sapiens, epithelial cell. CIL. Dataset
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Shown is a fluorescence microscopy image of a HeLa cell at mitotic metaphase. The cell is stained to reveal DNA (blue), microtubules (red), and the C-terminal portion of the KIF2A protein (green) which is largely confined to the compact chromosomes.
The image is part of a large project to characterize the locations of recombinantly tagged kinesin and myosin genes expressed from human or mouse-derived bacterial artificial chromosomes (BACs) as a resource for cell biology research.
See also: Maliga et al. 2013 A genomic toolkit to investigate kinesin and myosin motor funtion in cells. Nature Cell Biol; published online Feb 2013;DCI:10.1038/ncb2689.
图示为HeLa细胞在有丝分裂中期阶段的荧光显微镜图像。该细胞经过染色处理,以揭示DNA(蓝色)、微管(红色)以及KIF2A蛋白的C端部分(绿色),该部分主要局限于紧密的染色体上。此图像属于一项旨在描绘从人类或小鼠源细菌人工染色体(BACs)中表达的重排标记肌球蛋白和肌动蛋白基因位置的宏大项目,该项目将为细胞生物学研究提供资源。此外,可参见Maliga等人于2013年发表的《探究细胞中肌球蛋白和肌动蛋白马达功能的基因组工具包》。《自然细胞生物学》杂志;2013年2月在线发布;DCI:10.1038/ncb2689。
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CIL



