We sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for diff

NIAID Data Ecosystem10

Single-Cell Transcriptome Analysis Reveals Differential Signatures of Human Left-Sided and Right-Sided Colon

单细胞转录组学

左右结肠细胞差异

In our study, we obtained paired normal left-sided and right-sided colon mucosa tissues by colonoscopy, and 9,642 individual cells were analyzed by single-cell RNA-seq, which aims to explore the diffe

NIAID Data Ecosystem00

Single nuclei RNAseq analysis of HD mouse model and human brain reveals impaired 1 oligodendrocyte maturation and potential causal regulators. Single nuclei RNAseq analysis of HD mouse model and human brain reveals impaired 1 oligodendrocyte maturation and potential causal regulators

亨廷顿病少突胶质细胞成熟障碍

单细胞转录组学

A challenge in treating Huntington’s disease (HD) is the complexity of affected brain regions and cell types. We carried out a systematic analysis of cell type-specific changes in cortex and striatum

NIAID Data Ecosystem20

MTGR1 is required to maintain small intestinal stem cell populations - scRNA sequencing

小肠干细胞维持

单细胞转录组学

Loss of MTGR1 broadly skews intestinal cell lineages. Here, we used sc-RNA sequencing to analyze MTGR1-dependent changes in intestinal cell and stem cell populations. Cells from WT and Mtgr1 null duod

NIAID Data Ecosystem00

Rizzo 2022 Figure 4B CCR2+ cell Depletion

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