five

Tetrahymena thermophila Raw sequence reads

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https://www.ncbi.nlm.nih.gov/sra/SRP488050
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资源简介:
AMT2 and AMT5 were 6mA de novo methyltransferases of Tetrahymena thermophila. Knockout of AMT2 and/or AMT5 abolished methylation on a large majority of methylatable ApT genomic positions. The marked decrease in 6mA levels resulted in a significant reduction in the survival rates of sexual progenies, underscoring the importance of de novo 6mA in progeny development. To clarify the effects of AMT2/5 knockout on progeny, we employed RNA-seq.
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2025-04-23
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