Assessing the benefits of prescribed exercise in clinical populations

Interventions: Evidence-based exercise prescription. 26-week programme. Individualised programme and session frequency to match fitness level, disabilities and co-morbidities (likely range: 3 x per week to once per week). Clinical-gym setting supervised by clinical exercise physiologists. Some programmes may include a home-based exercise component when deemed safe to conduct. Clinical exercise physiologists will monitor patient adherence via patient maintained log books and phone calls. Primary outcome(s): Pre- post-intervention change in estimated VO2 maximum fromsubmaximal Astrand Ryhming cycle ergometer test[After 26 weeks of intervention];SF36v2.0 health questionnaire[After 26 weeks of intervention] Study Design: Purpose: Treatment; Allocation: Non-randomised trial; Masking: Open (masking not used);Assignment: Single group